Extra scrutiny for industry funded trials
نویسندگان
چکیده
منابع مشابه
Needed: closer scrutiny of clinical trials.
How many people know that eight patients in Hyderabad who were administered recombinant streptokinase to test its efficacy and safety have died? According to the Genetic Engineering Approval Committee (GEAC), the trial was being conducted by the drug’s manufacturer Shantha Biotechnics without taking clearance. Not surprisingly, the company denies the allegation claiming that it had taken permis...
متن کاملA meta-analysis comparing trials of antimuscarinic medications funded by industry or not.
OBJECTIVE To determine if there is a significant difference in outcomes of clinical trials funded by industry or not of antimuscarinic medications used to treat overactive bladder (OAB) symptoms and detrusor overactivity (DOA). METHODS A Medline search was conducted from January 1966 to June 2003 to identify human clinical trials of oxybutynin and tolterodine published in English. Randomized ...
متن کاملSurvey of public information about ongoing clinical trials funded by industry: evaluation of completeness and accessibility.
OBJECTIVE To evaluate the completeness and accessibility of public information about US clinical trials of drugs in development. DESIGN Review of online registers of clinical trials. DATA SOURCES Drugs in phase III trials were identified using three drug industry sources: PhRMA Survey, What's in the Pipeline, and the NDA Pipeline. Drug trials were then searched for on the following publicly...
متن کاملStandardised packaging and tobacco-industry-funded research.
www.thelancet.com Vol 384 July 19, 2014 233 Authors’ reply We thank Gerard Hanna and colleagues for their interest in our study, and agree it raises questions about the best sequence of treatments for patients with operable non-small-cell lung cancer. We found no difference in the number of complete resections b e t w e e n p a t i e n t s r e c e i v i n g chemotherapy compared with those rece...
متن کاملRecruitment to publicly funded trials — Are surgical trials really different?
BACKGROUND Good recruitment is integral to the conduct of a high-quality randomised controlled trial. It has been suggested that recruitment is particularly difficult for evaluations of surgical interventions, a field in which there is a dearth of evidence from randomised comparisons. While there is anecdotal speculation to support the inference that recruitment to surgical trials is more chall...
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ژورنال
عنوان ژورنال: BMJ
سال: 2005
ISSN: 0959-8138,1468-5833
DOI: 10.1136/bmj.331.7529.1350